Hinge Analysis

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We have a number of resources available for hinge analysis.

StoneHinge: StoneHinge is a hinge prediction algorithm that performs a network-based analysis of a single protein structure to detect hinge regions. StoneHinge incorporates both ProFlex, which uses the FIRST constraint counting algorithm, and DomDecomp, which uses Gaussian Normal Mode analysis.

HingeMaster: The new HingeMaster server predicts hinge locations in single protein structures. The algorithm combines FlexOracle, TLSMD, StoneHingeP and NSHP hinge predictors for maximum accuracy

RigidFinder: performs comparison of two protein conformations with the aim of identifying movable rigid regions.

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