Hinge Analysis

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We have a number of resources available for hinge analysis.

HingeMaster: This server predicts hinge locations in a single protein structure. The algorithm combines FlexOracle, TLSMD, StoneHingeP and NSHP hinge predictors for maximum accuracy.

RigidFinder: This tool performs comparison of two protein conformations with the aim of identifying movable rigid regions.

StoneHinge (currently under construction): A hinge prediction algorithm that performs a network-based analysis of a single protein structure to detect hinge regions. StoneHinge incorporates both ProFlex (which uses the FIRST constraint counting algorithm), and DomDecomp (which uses Gaussian Normal Mode analysis).

TACE Calculates pseudo-torsion angle changes in backbone structures given a pair of conformations.

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