Main Page
From Info
MolMovDB and Associated Tools
Contents |
Databases
- Protein motions: Manually curated descriptions of conformational changes in hundreds of distinct proteins, with references and movie links
- Movies: Thousands of morphs of transitions between PDB files, viewable through a Java applet or as MPEG or GIF movies. Most of these are submissions to the Morph Server by database users
- Search database
- The highlights page showcases some of our best movies
- [1]
- Collection of Sets of Motions
Servers
- Morph: A web-based tool for generating and animating chemically realistic interpolations between two conformations. Now supports RNA, DNA, and multi-subunit complexes
- Morph server FAQ WIKI
- Analysis of helix interactions
- Normal mode analysis: This tool allows the user to upload a query structure (or choose it from the motions database), calculate its lowest frequency Normal Mode, build the movie of this vibration and compare it with the pre-calculated flexibility regions based on either supplied B-factors or multiple structural alignment for the corresponding fold family (for single-domain queries)
- Hinge prediction: The new HingeMaster server predicts hinge locations in single protein structures. The algorithm combines FlexOracle, TLSMD, StoneHinge and NSHP hinge predictors for maximum accuracy
Other Useful Resources
- Macromolecular Geometry: Useful programs for structural analysis available for download
- Membrane protein motions: A web page for M Gerstein & C Chothia (1999), "Proteins in Motion"
- Large scale protein motions: Gerstein and Echols (2004)
- Protein-protein binding motions: Conformational changes associated with protein-protein interactions; Goh, Milburn and Gerstein (2004)
